Vitamin D3-driven signals for myeloid cell differentiation—Implications for differentiation therapy
نویسندگان
چکیده
منابع مشابه
1α,25-Dihydroxyvitamin D3–Induced Myeloid Cell Differentiation Is Regulated by a Vitamin D Receptor–Phosphatidylinositol 3-Kinase Signaling Complex
1alpha,25-dihydroxyvitamin D(3) (D(3)) promotes the maturation of myeloid cells and surface expressions of CD14 and CD11b, markers of cell differentiation in response to D(3). To examine how these responses are regulated, THP-1 cells were grown in serum-free medium and incubated with D(3). This was associated with rapid and transient increases in phosphatidylinositol 3-kinase (PI 3-kinase) acti...
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ژورنال
عنوان ژورنال: Leukemia Research
سال: 2010
ISSN: 0145-2126
DOI: 10.1016/j.leukres.2009.09.010